HETEROGENEOUS EXPRESSION AND SUBCELLULAR LOCALIZATION OF PYRUVATE DEHYDROGENASE COMPLEX IN PROSTATE CANCER

BackgroundPyruvate dehydrogenase (PDH) complex converts pyruvate into acetyl-CoA by pyruvate decarboxylation, which drives energy metabolism during cell growth, including prostate cancer (PCa) cell growth.The major catalytic subunit of PDH, PDHA1, is regulated by phosphorylation/dephosphorylation by pyruvate dehydrogenase kinases (PDKs) and pyruvat

Nowadays, there is a great deal of pressure and willingness on Quantum-mechanical twin paradox governments to expand the scope of their responsibilities from accounting to accountability.The impact of timely reporting is important in promoting accountability and increasing public confidence in the government.Therefore, this article examines the eff